Package: ssutil Title: Sample Size Calculation Tools Version: 1.2.0 Authors@R: c( person( given = "John J.", family = "Aponte", role = c("aut", "cre"), email = "john.j.aponte@gmail.com", comment = c(ORCID = "0000-0002-3014-3673")), person( given = "Chris", family = "Gast", email = "cgast@path.org", role = "ctb") ) Description: Functions for sample size estimation and simulation in clinical trials. Includes methods for selecting the best group using the Indifference-zone approach, as well as designs for non-inferiority, equivalence, and negative binomial models. For the sample size calculation for non-inferiority of vaccines, the approach is based on Fleming, Powers, and Huang (2021) . The Indifference-zone approach is based on Sobel and Huyett (1957) and Bechhofer, Santner, and Goldsman (1995, ISBN:978-0-471-57427-9). License: AGPL (>= 3) Encoding: UTF-8 Roxygen: list(markdown = TRUE) Depends: R (>= 4.1) Suggests: knitr, rmarkdown, spelling, testthat (>= 3.0.0) Language: en-US Imports: stats, stringr, broom, MASS, mvtnorm, tibble Config/testthat/edition: 3 VignetteBuilder: knitr URL: https://johnaponte.github.io/ssutil/, https://github.com/johnaponte/ssutil BugReports: https://github.com/johnaponte/ssutil/issues Config/roxygen2/version: 8.1.0 Config/pak/sysreqs: libicu-dev Repository: https://johnaponte.r-universe.dev Date/Publication: 2026-09-17 15:42:25 UTC RemoteUrl: https://github.com/johnaponte/ssutil RemoteRef: HEAD RemoteSha: 765669b0c9830f4dfe34d1f3e000db1dd4a86c48 NeedsCompilation: no Packaged: 2026-09-20 12:09:04 UTC; root Author: John J. Aponte [aut, cre] (ORCID: ), Chris Gast [ctb] Maintainer: John J. Aponte